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Awesome post!! READ! πŸ§˜β€οΈπŸ§ οΈ @guz_unplugged β€’ β€’ β€’ #repost @ryansoulution1.618 ・・・ DMT may play an even wider biological role. The authors of the review highlight that the latest molecular target that binds to DMT, known as the Sigma-1R receptor, may be a critical nexus point in DMT’s therapeutic effects relative to many common disease states. * The Sigma-1R receptor is essential for managing intracellular stress and can be found in various tissues such as the brain, retina, liver, lung, heart, and immune system. Sigma-1R is a special kind of protein receptor that is known as a molecular chaperone, or a protein that has the function of helping other proteins fold correctly into their three dimensional conformations, especially under stressful situations. Many diseases are associated with dysfunctional chaperones and the Sigma-1R receptor/chaperone has been linked toΒ multiple #diseasesΒ such as #alzheimers, #Parkinson’s, #cancer, #cardiomyopathy, retinal dysfunction, perinatal and #traumaticBrainInjury, frontal motor #neurondegeneration, amyotrophic lateral sclerosis, HIV-related #dementia, major #depression, and psychostimulant #addiction, to name a few. * As DMT naturally binds to the Sigma-1R receptor, the authors have suggested that DMT may also have a physiological role beyond its psychoactivity and posit that DMT may elicit cell protective effects by acting on Sigma-1R. Some of these protective effects include restoration of neurons and modulation of immunity. * Read more at reset.me!! * Stay relevant with #psychedelicresearch following folks like @sophiarokhlin & @mapsnews #DMT #therapeuticdrugs #themoreyouknow #staypositive #Psychedelics #ayahuasca #bigpharma #stress #gooddrugs #knowmore #nomorepills #health #stayhealthy

psychedelics photo

Soma, Gordon Wasson, 1968. First, limited issue: 680 numbered copies handset and printed letterpress on handmade paper, bound in quarter leather in publisher’s slipcase. 30% off during sale. #psychedelics #magicmushrooms #ethnography #entheogen #mycology #ethnomycology #vedic #wendydonigeroflaherty #gordonwasson #limitededition Holiday Clearance Sale at Passages Bookshop! 30% off all books, plus 50-75% off markdowns in all categories, and all framed art. Through Dec. 21. In-store only. Hours Thu-Sat 12-6. FB: PassagesBookshop #portlandoregon #portlandoregonart #usedbooks #usedbookstores #rarebooks #rarebookshop #graphicart

psychedelics photo

DMT may play an even wider biological role. The authors of the review highlight that the latest molecular target that binds to DMT, known as the Sigma-1R receptor, may be a critical nexus point in DMT’s therapeutic effects relative to many common disease states. * The Sigma-1R receptor is essential for managing intracellular stress and can be found in various tissues such as the brain, retina, liver, lung, heart, and immune system. Sigma-1R is a special kind of protein receptor that is known as a molecular chaperone, or a protein that has the function of helping other proteins fold correctly into their three dimensional conformations, especially under stressful situations. Many diseases are associated with dysfunctional chaperones and the Sigma-1R receptor/chaperone has been linked toΒ multiple #diseasesΒ such as #alzheimers, #Parkinson’s, #cancer, #cardiomyopathy, retinal dysfunction, perinatal and #traumaticBrainInjury, frontal motor #neurondegeneration, amyotrophic lateral sclerosis, HIV-related #dementia, major #depression, and psychostimulant #addiction, to name a few. * As DMT naturally binds to the Sigma-1R receptor, the authors have suggested that DMT may also have a physiological role beyond its psychoactivity and posit that DMT may elicit cell protective effects by acting on Sigma-1R. Some of these protective effects include restoration of neurons and modulation of immunity. * Read more at reset.me!! * Stay relevant with #psychedelicresearch following folks like @sophiarokhlin & @mapsnews #DMT #therapeuticdrugs #themoreyouknow #staypositive #Psychedelics #ayahuasca #bigpharma #stress #gooddrugs #knowmore #nomorepills #health #stayhealthy